QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.

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TAMs: PotentialTumor Biomarkers

Tumor-associated macrophages (TAMs) are a type of cell that is found within most tumor masses. Circulating tumor cells (CTC) are shed from a primary tumor and circulate in the bloodstream. Some scientists believe that TAMs derived from primary tumors facilitate…

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Genetic Research: A Way Forward for Prostate Cancer

Using Genetics to Prevent Delayed Biopsies in African American Men Dr. Catalona and other researchers conducted a study to evaluate whether genetic correction using genetic variants could reduce potentially unnecessary and/or delayed biopsies in African-American men. Certain genetic variants have…

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FDA ALERT: Hidden Drugs in Dietary Supplements

According to the U.S. Food and Drug Administration (FDA), some dietary supplements marketed to treat erectile dysfunction or enhance sexual performance may contain prescription drugs or undisclosed ingredients that could be harmful. These products are typically represented as being “all…

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Decoding the Genetics of a Nation

Dr. Catalona’s research group has a long-standing collaboration with deCODE genetics, Inc. In this collaboration, they discovered the first genetic variant associated with prostate cancer susceptibility in 2006, and helped discover and validate a dozen more of the 105 known…

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